Gene News and Research

Latest Gene News and Research

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

A groundbreaking study led by experts from Indiana University School of Medicine has shed new light on the genetic underpinnings of Alzheimer's disease.

6 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

To reimagine existing preclinical trials for Alzheimer's disease, University of Pittsburgh School of Medicine neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmoset monkeys, outlining their approach in Alzheimer's & Dementia: Translational Research & Clinical Interventions.

6 Sep 2023

Study reveals heart failure insights at single-cell level

Researchers examined the cell-intrinsic effects of hematopoietic stem cells with somatic mutations in circulating cells from heart failure patients.

6 Sep 2023

Clovibactin - a game-changing novel antibiotic with no resistance

Researchers reported the discovery of a new antibiotic, clovibactin.

6 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Study identifies potential target for reversing drug resistance in ovarian cancer

For the 314,000 people diagnosed with ovarian cancer each year, hope often comes in the form of platinum-based drugs such as cisplatin.

5 Sep 2023

ADHD linked to risk for several common and serious mental health issues

The hyperactivity disorder, usually referred to as ADHD, is an independent risk factor for several common and serious mental health issues, finds research published in the open access journal BMJ Mental Health.

5 Sep 2023

Gut feeling: How your microbiome could be shaping your mental health

Researchers in Biological Psychiatry delve into the complex relationship between the gut microbiome and mental health disorders like depression and bipolar disorder. The study explores how not just gut bacteria, but also lesser-known gut microorganisms such as viruses, fungi, and parasites, play a pivotal role in mood disorders.

5 Sep 2023

Sex hormones drive differences in male and female mouse kidneys

Female kidneys are known to be more resilient to disease and injury, but males need not despair. A new USC Stem Cell-led study published in Developmental Cell describes not only how sex hormones drive differences in male and female mouse kidneys, but also how lowering testosterone can "feminize" this organ and improve its resilience.

5 Sep 2023

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study published in Science Signaling led by researchers at NYU College of Dentistry.

5 Sep 2023

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Around 5.2% of the global population carries abnormal hemoglobin genes. Each year, 300,000 to 500,000 children are born with severe hemoglobinopathies worldwide, with approximately 80% of these cases occurring in developing countries.

5 Sep 2023

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Researchers have developed a new blood test that measures mitochondrial DNA damage as a potential marker for Parkinson's disease (PD). The study shows the test could aid in diagnosing PD and assessing responses to LRRK2 kinase inhibitors, which may help in reducing mitochondrial damage in PD patients.

4 Sep 2023

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Researchers presented serological evidence of highly pathogenic avian influenza (HPAI) H5N1 virus infection in a pet cat and five dogs on a rural poultry farm in Italy.

4 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

Silencing two genes can make cancer cells receptive to chemotherapy

Scientists from Queen Mary University of London have discovered two new genes that cause head and neck cancer patients to be resistant to chemotherapy, and that silencing either gene can make cancer cells previously unresponsive to chemotherapy subsequently respond to it.

4 Sep 2023

The first point-of-care genetic test for lactose intolerance: A compact, lab-on-phone diagnostic assay

The performance of a compact diagnostic assay that can accurately and rapidly diagnose lactose intolerance.

4 Sep 2023

Big Tuna and automated buffer exchange: An interview with Unchained Labs

In this interview, AZoNetwork speaks with Joe Barco, the Senior Director of Workflow Marketing at Unchained Labs, about the benefits of automated buffer exchange with Big Tuna.

From Unchained Labs 4 Sep 2023

Some communities express mistrust and cynicism in response to conversations about genomics

New research published today in Human Genetics and Genomics Advances reveals the difference between ‘what we say’ and ‘what people hear’ when engaging underrepresented communities around genomics and healthcare.

4 Sep 2023

Innovate UK funding to support the development of powdered gene therapy for bone graft augmentation

TherageniX, a University of Nottingham spin out pioneering a dry powder gene therapy formulation for bone graft augmentation, and its collaborator, the University of Nottingham, have been awarded a £995,000 grant from Innovate UK, the UK’s innovation agency.

4 Sep 2023

Gene News and Research

Latest Gene News and Research

IU study sheds new light on the genetic underpinnings of Alzheimer's disease

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Pitt neuroscientists create first non-human primate model of hereditary Alzheimer's in marmosets

Study reveals heart failure insights at single-cell level

Clovibactin - a game-changing novel antibiotic with no resistance

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Study identifies potential target for reversing drug resistance in ovarian cancer

ADHD linked to risk for several common and serious mental health issues

Gut feeling: How your microbiome could be shaping your mental health

Sex hormones drive differences in male and female mouse kidneys

Targeting the ORAI1 calcium channel could provide new approach to treating oral cancer

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

New blood test pinpoints Parkinson's disease through mitochondrial DNA damage

Study reports highly pathogenic avian influenza A infection in pet dogs and cat on a rural poultry farm in Italy

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Silencing two genes can make cancer cells receptive to chemotherapy

The first point-of-care genetic test for lactose intolerance: A compact, lab-on-phone diagnostic assay

Big Tuna and automated buffer exchange: An interview with Unchained Labs

Some communities express mistrust and cynicism in response to conversations about genomics

Innovate UK funding to support the development of powdered gene therapy for bone graft augmentation

eBook: Using iPSCs models for human disease research and drug discovery eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson