Gene News and Research

Latest Gene News and Research

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Researchers across Europe have delved into the DNA methylation patterns in CD4+ T-cells of psoriasis and psoriatic arthritis (PsA) patients, unveiling potential new biomarkers for these conditions. Their study suggests that these unique profiles could serve as both diagnostic and prognostic tools, although further validation is needed for real-world clinical application.

10 Sep 2023

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Tiziana Life Sciences Ltd. (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies via novel routes of drug delivery, today announced acceptance of a publication, “Nasal Administration of anti-CD3 monoclonal antibody (mAb) ameliorates disease in a mouse model of Alzheimer’s disease”, in the preeminent journal, Proceedings of the National Academy of Sciences (PNAS), that supports foralumab’s mechanism as a potential treatment for Alzheimer’s disease (AD), a difficult-to-treat neuroinflammatory disease.

9 Sep 2023

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin.

8 Sep 2023

Brain-blood barrier found to play a key role in governing ant behavior

The blood-brain barrier (BBB) has been found to play a significant role in controlling behavior critical to how ant colonies function, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

8 Sep 2023

Researchers use machine learning to predict drug approval chances before clinical trials

Developing new drugs is paramount in discovering innovative treatments and preventing diseases. This is vital not only for advancing medicine but also for the overall health and well-being of humanity.

8 Sep 2023

Latest updates on SARS-CoV-2 variants identified in the UK

The UK Health Security Agency (UKHSA) has published SARS-CoV-2 variant surveillance and assessment technical briefing 53. It contains the latest epidemiological and genomic analysis of the emergent BA.2.86 variant.

8 Sep 2023

FAU researchers discover novel method to identify therapeutic agents to treat addiction

According to the Substance Abuse and Mental Health Services Administration, approximately 40 million people in the United States had a substance use disorder in 2020.

8 Sep 2023

Largest-ever study looks into the genetics of random "round-the-clock" blood glucose levels

Groundbreaking research published today in Nature Genetics describes the largest-ever study into the genetics of random "round-the-clock" blood glucose levels.

8 Sep 2023

The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Vibrant green leaves sprout from tall fragrant plants sitting neatly in two rows of terracotta pots in Valerie Sponsel's UTSA biology laboratory.

8 Sep 2023

Promising new cervical cancer test fills in the gap missed by Pap tests

Researchers assessed a novel human papillomavirus (HPV) and host deoxyribonucleic acid (DNA) methylation score for adenocarcinoma in-situ (AIS) and cervical adenocarcinoma (ADC) screening.

8 Sep 2023

Ohio State University Wexner Medical Center administers first targeted gene therapy for ALS

The Ohio State University Wexner Medical Center is one of the first nationwide to administer a targeted gene therapy for patients with a specific form of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

8 Sep 2023

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

New genetic factors that affect the plasma apolipoprotein E levels.

8 Sep 2023

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

The interaction of caffeine with Leucine rich repeat kinase 2 (LRRK2) genetic risk variants in Asians.

8 Sep 2023

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

With obesity rates projected to continue rising globally, there is an urgent need to understand the intricate mechanisms that contribute to metabolic diseases such as diabetes.

8 Sep 2023

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Scientists at St. Jude Children’s Research Hospital found that a subset of CD8+ T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer’s disease.

8 Sep 2023

Novel test could improve detection of cervical adenocarcinoma

In findings with potentially important implications for cervical cancer screening, scientists at the National Cancer Institute (NCI)-designated Montefiore Einstein Cancer Center (MECC) have developed a test for detecting a type of cervical cancer that Pap tests often miss.

7 Sep 2023

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

The research paper delves into the role of brown adipose tissue and its protein, UCP1, in diet-induced thermogenesis, questioning whether it could be a key to fighting obesity. Despite some evidence suggesting that brown fat activity could influence weight, the study calls for more research to determine the causality between reduced brown adipose tissue activity and obesity.

7 Sep 2023

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

7 Sep 2023

Newly discovered nanobody may lead to a treatment for Retinitis Pigmentosa

A team of scientists from the University of California, Irvine, believe they have discovered a special antibody which may lead to a treatment for Retinitis Pigmentosa, a condition that causes loss of central vision, as well as night and color vision.

7 Sep 2023

Gene News and Research

Latest Gene News and Research

Is DNA methylation the missing link in diagnosing and treating psoriasis and psoriatic arthritis?

Study evaluating intranasal anti-CD3 for treatment of Alzheimer’s disease published in the PNAS journal

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Brain-blood barrier found to play a key role in governing ant behavior

Researchers use machine learning to predict drug approval chances before clinical trials

Latest updates on SARS-CoV-2 variants identified in the UK

FAU researchers discover novel method to identify therapeutic agents to treat addiction

Largest-ever study looks into the genetics of random "round-the-clock" blood glucose levels

The role of exercise-induced hormone irisin in amyloid beta reduction

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Promising new cervical cancer test fills in the gap missed by Pap tests

Ohio State University Wexner Medical Center administers first targeted gene therapy for ALS

Breakthrough genome-wide study uncovers new loci impacting apolipoprotein E levels and Alzheimer's risk

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

Unraveling the relationship between obesity-related metabolic dysfunction and endotrophin

A subset of CD8+ T cells can play a protective role against Alzheimer’s disease pathogenesis

Novel test could improve detection of cervical adenocarcinoma

Can brown fat really keep you slim? New study digs into the science of diet-induced thermogenesis

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Newly discovered nanobody may lead to a treatment for Retinitis Pigmentosa

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

PhD researcher at LifeArc

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