Gene News and Research

Latest Gene News and Research

Study uncovers unique genetic diversity in Australian Indigenous populations

Scientists at ANU have revealed significant genetic diversity among Australian Indigenous communities, uncovering unique genetic variations that could impact personalized medical treatments for chronic diseases.

14 Dec 2023

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

In a novel study, researchers from the Icahn School of Medicine at Mount Sinai introduced LoGoFunc, an advanced computational tool that predicts pathogenic gain- and loss-of-function variants across the genome.

14 Dec 2023

Advancements in food allergy research promise improved diagnosis and treatment options

A review in the Journal of Allergy and Clinical Immunology discusses the global trends in food allergy prevalence, with stabilization in developed regions and an increase in developing countries, alongside advancements in understanding the mechanisms, diagnosis, and treatment of food allergies.

13 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

CRISPR opens doors for novel probiotic functions and applications

Humans can benefit significantly from symbiotic relationships with probiotics - live bacteria and microorganisms that influence the gut microbiota.

13 Dec 2023

Understanding how proteasome dysfunction contributes to age-related cognitive decline

About 40 percent of people over age 65 suffer some form of age-related memory loss, which puts them at higher risk for developing dementia and Alzheimer's disease.

13 Dec 2023

Genetic link to premature ovarian insufficiency explained: A mitochondrial perspective

Infertility affects around 48 million couples worldwide and can have various causes. In mammals, including humans, eggs are produced in the ovary.

13 Dec 2023

Epigenetic changes can contribute to the development of type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Protective genetic variant shields Black Americans from kidney disease risk

Many Black Americans who are thought to have a high risk of developing kidney disease possess a protective genetic variant that nullifies the extra risk, a new study from Columbia researchers has found.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

In a study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, patients recently diagnosed with a common and aggressive form of acute myeloid leukemia reported having improved quality of life when a newly approved drug was part of the treatment plan.

11 Dec 2023

Research uncovers potential treatment target for rare, genetic type of epilepsy

Researchers at the Francis Crick Institute, UCL and MSD have identified a potential treatment target for a genetic type of epilepsy.

11 Dec 2023

Colombian family's Alzheimer's anomaly offers insights into disease pathogenesis and prevention

Alzheimer's disease has plagued one large Colombian family for generations, striking down half of its members in the prime of life.

11 Dec 2023

UB research identifies key mechanism in infantile cystinosis

University at Buffalo research has identified how a misstep in the genesis of a key component of the kidney causes infantile cystinosis, a rare disease that significantly shortens the lifespan of patients.

11 Dec 2023

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

A Stanford Medicine-led, international study of hundreds of samples from patients with Hodgkin lymphoma has shown that levels of tumor DNA circulating in their blood can identify who is responding well to treatment and others who are likely to experience a disease recurrence - potentially letting some patients who are predicted to have favorable outcomes forgo lengthy treatment.

11 Dec 2023

Gene News and Research

Latest Gene News and Research

Study uncovers unique genetic diversity in Australian Indigenous populations

Novel machine learning tool predicts gain- and loss-of-function variants across the genome

Advancements in food allergy research promise improved diagnosis and treatment options

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

CRISPR opens doors for novel probiotic functions and applications

Understanding how proteasome dysfunction contributes to age-related cognitive decline

Genetic link to premature ovarian insufficiency explained: A mitochondrial perspective

Epigenetic changes can contribute to the development of type 2 diabetes

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Protective genetic variant shields Black Americans from kidney disease risk

UVA atlas unveils cellular blueprint of atherosclerosis

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Quizartinib extends life and enhances wellbeing for AML patients with key mutation

Research uncovers potential treatment target for rare, genetic type of epilepsy

Colombian family's Alzheimer's anomaly offers insights into disease pathogenesis and prevention

UB research identifies key mechanism in infantile cystinosis

Study reveals genetic roots of hodgkin lymphoma, offering hope for new treatments

MIT scientists develop nanoparticles to reduce inflammation in the brain

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

New drug combo shows promise in targeting RAS-mutant multiple myeloma

eBook: Using iPSCs models for human disease research and drug discovery eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson