Gene News and Research

Latest Gene News and Research

GLP-1 drugs calm inflammation beyond diabetes and weight loss

This Journal of Clinical Investigation review describes how glucagon-like peptide-1 (GLP-1)–based medicines reduce systemic and tissue inflammation through both weight-dependent and weight-independent mechanisms. It details preclinical and clinical evidence linking GLP-1 receptor activation to cardiovascular, renal, hepatic, neural, and joint anti-inflammatory effects while outlining uncertainties and future research needs.

4 Nov 2025

Redefining aging as an evolutionary achievement

In our modern society, aging tends to be something we ignore, and then try to avoid. Mainstream culture is geared toward the young, using the youth to gauge trends and styles, and targeting their spending power.

4 Nov 2025

Motor protein Myosin II regulates temperature sensitivity of immune cells

Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level-until now.

4 Nov 2025

Stress hormones may silence crucial neuronal genes through specific RNA molecules

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

4 Nov 2025

NIH-funded study investigates signals mediating the earliest stages of cancer development

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it.

4 Nov 2025

How walnuts combat inflammation and oxidative stress in the body

This review in Food Science & Nutrition synthesizes evidence showing that walnuts (Juglans regia L.) exert potent antioxidant, anti-inflammatory, apoptosis-regulatory, and immunomodulatory effects through bioactive compounds influencing mitochondrial, cytokine, and redox pathways.

3 Nov 2025

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Acute myeloid leukemia driven by tandem duplications within the UBTF gene (UBTF-TD AML) is a high-risk pediatric cancer in urgent need of novel therapeutic options.

3 Nov 2025

Large-scale foundation model reconstructs how cells interact within tissues

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics.

3 Nov 2025

Researchers develop a versatile tool for controlling gene activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

3 Nov 2025

New genomic method enables multiple people with rare conditions to receive diagnoses

A new genomic method has enabled multiple people with rare conditions to receive diagnoses that were previously unattainable by identifying complex structural genetic changes that are often missed by standard tests.

3 Nov 2025

Atrial dysfunction assessment tool may help identify stroke risk in people with ATTR-CM

A hidden atrial dysfunction may raise stroke risk in people with transthyretin amyloid cardiomyopathy (ATTR-CM); however, a non-invasive assessment tool may help identify those at increased risk, according to a preliminary study to be presented at the American Heart Association's Scientific Sessions 2025.

3 Nov 2025

Better schools can offset genetic disadvantages in learning

Research indicates that high-quality schooling can compensate for genetic disparities in reading success, underscoring the importance of equitable education.

3 Nov 2025

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

Researchers identified five previously unknown genes linked to obesity by analyzing rare protein-truncating variants across six ancestries. The study reveals how rare and common genetic factors combine to influence BMI and related diseases like diabetes and heart failure.

2 Nov 2025

GeneSight test-guided treatment leads to faster remission and response in patients with depression

Myriad Genetics, Inc., a leader in molecular diagnostic testing and precision medicine, today announced a post-hoc analysis of the Precision Medicine in Mental Health Care (PRIME) study showed that treatment informed by the GeneSight® test led to faster initial remission and response in patients with Major Depressive Disorder (MDD).

31 Oct 2025

Study reveals how melanoma evolves to resist immunotherapy

A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse that resistance.

31 Oct 2025

Neuroscientists uncover a surprising role for "Frazzled" protein in the nervous system of fruit flies

Florida Atlantic University neuroscientists have uncovered a surprising role for a protein named "Frazzled" (known as DCC in mammals) in the nervous system of fruit flies, showing how it helps neurons connect and communicate with lightning speed.

31 Oct 2025

Genetic insights into vestibular system damage from ototoxic drugs

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance and other motor skills.

31 Oct 2025

Breakthrough study maps impact of thousands of variants in heart disease gene

An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease.

31 Oct 2025

How nerve cells in the gut adapt to microbial and immune challenges

Ramnik Xavier, MD, PhD, of the Department of Molecular Biology at Massachusetts General Hospital, is the senior author of a paper published in Science, "Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation."

31 Oct 2025

Researchers visualize how brain network development is altered in rare childhood disorder

Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder.

31 Oct 2025

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Gene News and Research

Latest Gene News and Research

GLP-1 drugs calm inflammation beyond diabetes and weight loss

Redefining aging as an evolutionary achievement

Motor protein Myosin II regulates temperature sensitivity of immune cells

Stress hormones may silence crucial neuronal genes through specific RNA molecules

NIH-funded study investigates signals mediating the earliest stages of cancer development

How walnuts combat inflammation and oxidative stress in the body

St. Jude scientists identify new therapeutic target for high-risk pediatric leukemia

Large-scale foundation model reconstructs how cells interact within tissues

Researchers develop a versatile tool for controlling gene activity

New genomic method enables multiple people with rare conditions to receive diagnoses

Atrial dysfunction assessment tool may help identify stroke risk in people with ATTR-CM

Better schools can offset genetic disadvantages in learning

Scientists uncover new obesity genes that reshape understanding of weight and disease risk

GeneSight test-guided treatment leads to faster remission and response in patients with depression

Study reveals how melanoma evolves to resist immunotherapy

Neuroscientists uncover a surprising role for "Frazzled" protein in the nervous system of fruit flies

Genetic insights into vestibular system damage from ototoxic drugs

Breakthrough study maps impact of thousands of variants in heart disease gene

How nerve cells in the gut adapt to microbial and immune challenges

Researchers visualize how brain network development is altered in rare childhood disorder

Genomics - Industry Focus eBook (2nd edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production