Gene News and Research

Latest Gene News and Research

Common antibiotic can improve survival and neurological outcomes in CNS-TB

Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated that doxycycline, a commonly available and inexpensive antibiotic, can improve survival rates and neurological outcomes in Central Nervous System Tuberculosis (CNS-TB) in a preclinical non-human study.

12 Nov 2025

Shift Bioscience publishes improved metric calibration framework for robust genetic perturbation modeling using AI Virtual Cells

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to end the morbidity and mortality of aging, today announced the release of new research detailing an improved framework for evaluating benchmark metric calibration in virtual cell models. U

From Shift Bioscience 11 Nov 2025

Utah researchers uncover microglia as key regulators of anxiety in the brain

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide.

11 Nov 2025

AI chat box helps investigate complex biology in English language

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

11 Nov 2025

Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

In a new Northwestern Medicine study, scientists have developed a more precise genetic risk score to determine whether a person is likely to develop arrhythmia, an irregular heartbeat that can lead to serious conditions such as atrial fibrillation (AFib) or sudden cardiac death.

11 Nov 2025

New precision therapies reshape the future of pancreatitis treatment

Pancreatitis remains a major global health burden, encompassing acute pancreatitis (AP), chronic pancreatitis (CP), and autoimmune pancreatitis (AIP).

11 Nov 2025

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Alzheimer's Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments have been found that can halt or reverse the progression of this devastating disease.

11 Nov 2025

Study uncovers new mechanism for chromosome congression during mitosis

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell division. The study demonstrates that two motor proteins, KIF18A and CENP-E, act cooperatively to ensure proper chromosome congression. Remarkably, simultaneous inhibition of these proteins selectively kills cancer cells, suggesting a promising therapeutic avenue.

10 Nov 2025

Micro-RNA in sperm proves vital for human embryogenesis

The sperm is not a passive supplier of genetic material to the egg. A study from Linköping University, Sweden, shows that certain molecules that come with the sperm, so-called micro-RNA, contribute to the development of the embryo several days after conception. The findings, published in the journal Nature Communications, may in the long term contribute to better diagnosis and treatment of involuntary childlessness.

10 Nov 2025

Study advances the possibility of age-based pancreatic cancer treatment

While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging is not one of them. In the case of pancreatic cancer, it also can limit treatment options if a patient is too frail to be safely treated with surgery or other alternatives.

10 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available.

10 Nov 2025

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes.

10 Nov 2025

Maternal type 1 diabetes may protect children from developing the disease

Findings suggest maternal T1D exposure leads to protective epigenetic alterations in children, influencing immune response and type 1 diabetes susceptibility.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

Condensate-based strategy protects synthetic gene circuits across cell generations

Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing the synthetic gene circuits to lose their new functions.

7 Nov 2025

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients through a collaboration with Boston Children's Hospital.

7 Nov 2025

Comprehensive kinase atlas reveals new insights into cell signaling and disease

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

New initiative focuses on advancing human disease research through AI and frontier biology

Mark Zuckerberg and Priscilla Chan today announced the launch of a first-of-its-kind initiative combining frontier artificial intelligence and frontier biology to dramatically accelerate scientific progress toward understanding and addressing human disease.

7 Nov 2025

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Gene News and Research

Latest Gene News and Research

Common antibiotic can improve survival and neurological outcomes in CNS-TB

Shift Bioscience publishes improved metric calibration framework for robust genetic perturbation modeling using AI Virtual Cells

Utah researchers uncover microglia as key regulators of anxiety in the brain

AI chat box helps investigate complex biology in English language

Northwestern scientists create new genetic risk score to improve prediction of arrhythmia

New precision therapies reshape the future of pancreatitis treatment

Targeting RNA splicing errors protects against tau-induced neurodegeneration

Study uncovers new mechanism for chromosome congression during mitosis

Micro-RNA in sperm proves vital for human embryogenesis

Study advances the possibility of age-based pancreatic cancer treatment

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Maternal type 1 diabetes may protect children from developing the disease

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Condensate-based strategy protects synthetic gene circuits across cell generations

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Comprehensive kinase atlas reveals new insights into cell signaling and disease

New initiative focuses on advancing human disease research through AI and frontier biology

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production