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Study reveals abelacimab’s potential to improve anticoagulation safety for AFib patients

Abelacimab, a factor XI inhibitor, demonstrated a 62–69% reduction in major bleeding compared to rivaroxaban in atrial fibrillation patients at moderate-to-high stroke risk, with comparable safety and efficacy. While ischemic stroke rates were slightly higher, they were not statistically significant, warranting further phase 3 trials for confirmation.

23 Jan 2025

Researchers map genetic differences across children with Wilms tumor

Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.

23 Jan 2025

Metronomic chemotherapy offers hope for children with neuroblastoma

Neuroblastoma is the most common extracranial solid tumor in children, with nearly 50% of cases diagnosed at an advanced stage, often with metastatic disease.

23 Jan 2025

Empa researchers improve epidemic forecasts with reproduction matrix

The reproduction number R is often used as an indicator to predict how quickly an infectious disease will spread.

23 Jan 2025

Study links chemesthetic sensitivity to food preferences and consumption

Oral chemesthesis, or chemically induced tactile sensation in the mouth area, affects the consumption and recalled pleasantness of certain foods and drinks, such as chilli sauce and alcoholic beverages.

23 Jan 2025

New genomic insights could transform bipolar disorder treatment

Study published in Nature identifies nearly 300 genomic regions associated with bipolar disorder, and 36 key genes involved in the disease.

23 Jan 2025

What causes behavioral side effects in popular weight loss drugs?

The study of GLP1R variants shows associations with cardiometabolic traits and behavioral changes, highlighting indirect effects of GLP1RA on mental health.

23 Jan 2025

Researchers investigate a new combination therapy against cancer

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer.

23 Jan 2025

Prehabilitation associated with fewer complications and improved recovery after surgery

Actively preparing for major surgery by exercising and improving diet (known as "prehabilitation") is associated with fewer complications, less time in hospital, and improved recovery and quality of life in adults, finds an analysis of clinical trials published by The BMJ today.

23 Jan 2025

Adults with ADHD found to have reduced life expectancy

Adults who have been diagnosed with attention deficit hyperactivity disorder (ADHD) may be living shorter lives than they should, finds a world-first study led by UCL researchers.

23 Jan 2025

Multiple sclerosis linked to increased risk of perinatal mental illness

People with multiple sclerosis (MS) face a significantly higher risk of perinatal mental illness compared to those with other chronic conditions, according to a new study analyzing over 890,000 births in Ontario.

23 Jan 2025

Study reveals potential drug links to Dementia risk

Findings from a large-scale review indicate certain medications may influence dementia risk, offering insights for prevention and drug repurposing strategies.

23 Jan 2025

Prehabilitation may improve surgical recovery and reduce complications

A new study published in The BMJ suggests that prehabilitation (also called prehab) may be able to reduce complications and length of hospitalization after surgery, while also improving quality of life and physical recovery.

23 Jan 2025

New diagnostic device could enable at-home early bladder cancer detection

Innovative fluorescence-based diagnostic system identifies early-stage bladder cancer with 90% accuracy, utilizing untreated urine samples for at-home testing.

23 Jan 2025

Study links PTSD and anxiety to lower ovarian reserve in women firefighters

A new study led by University of Arizona Mel and Enid Zuckerman College of Public Health researchers in collaboration with fire service partners and other researchers around the country through the Fire Fighter Cancer Cohort Study showed that post-traumatic stress disorder and anxiety are associated with lower levels of anti-Müllerian hormone, a marker of ovarian reserve, among women firefighters.

22 Jan 2025

New study links intestinal protein to food allergy development

When is food simply nourishing and enjoyable, and when does it provoke an allergic reaction? The answer appears to lie in the balance of microbes that live in our intestine - and a specific protein secreted by intestinal goblet cells that influences that balance.

22 Jan 2025

Study finds sharp increase in mental health admissions among children in England

There was a 65% increase in the number of children and young people being admitted to general acute medical wards in hospitals in England because of a mental health concern between 2012 and 2022, finds a new study led by UCL researchers.

22 Jan 2025

Study reveals racial and ethnic differences in children's sleep patterns

Researchers from Michigan State University's Department of Human Development and Family Studies revealed that sleep patterns may vary across different racial and ethnic groups - notably for non-white and multiracial children.

22 Jan 2025

Maternal vitamin D deficiency may accelerate fetal aging and impact newborn health

Maternal vitamin D deficiency during pregnancy is linked to accelerated epigenetic gestational age in infants at birth, suggesting improper fetal development influenced by low vitamin D levels. The study also found associations between maternal age, birth height, and epigenetic aging, though cord blood vitamin D showed no significant impact.

22 Jan 2025

Researchers construct a detailed structural map of GABAA receptors in the human brain

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other.

22 Jan 2025

Medical Research News

Study reveals abelacimab’s potential to improve anticoagulation safety for AFib patients

Researchers map genetic differences across children with Wilms tumor

Metronomic chemotherapy offers hope for children with neuroblastoma

Empa researchers improve epidemic forecasts with reproduction matrix

Study links chemesthetic sensitivity to food preferences and consumption

New genomic insights could transform bipolar disorder treatment

What causes behavioral side effects in popular weight loss drugs?

Researchers investigate a new combination therapy against cancer

Prehabilitation associated with fewer complications and improved recovery after surgery

Adults with ADHD found to have reduced life expectancy

Multiple sclerosis linked to increased risk of perinatal mental illness

Study reveals potential drug links to Dementia risk

Prehabilitation may improve surgical recovery and reduce complications

New diagnostic device could enable at-home early bladder cancer detection

Study links PTSD and anxiety to lower ovarian reserve in women firefighters

New study links intestinal protein to food allergy development

Study finds sharp increase in mental health admissions among children in England

Study reveals racial and ethnic differences in children's sleep patterns

Maternal vitamin D deficiency may accelerate fetal aging and impact newborn health

Researchers construct a detailed structural map of GABAA receptors in the human brain

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