Axxam S.p.A. is a Contract Research Organization (CRO) providing integrated early discovery services to the Life Sciences sector. We support pharmaceutical and biotechnology companies, start-ups, patient foundations, and academic institutions throughout their journey from target identification to lead generation, across all therapeutic areas and target classes.
Axxam is a biology powerhouse, translating innovative science into bioactive molecules. Our integrated target-based drug discovery offering, known as DiscoveryMAXX, spans target identification and validation, assay development, hit identification through high-throughput screening using Axxam’s high-quality synthetic and natural compound collections or client-provided libraries, hit validation, hit-to-lead activities, and compound management.
DiscoveryMAXX is founded on the principle that better decisions early in drug discovery significantly reduce the risk of downstream failure, delays, and budget overruns during preclinical and clinical development.
In addition to pharmaceutical and biotechnology projects, we apply the same rigorous scientific approach to identify novel bioactive compounds for crop protection, animal health, food and beverage, pet food, cosmetics, and fragrance industries.
For more information, please visit www.axxam.com.
Capabilities and expertise
- Our capabilities cover the full continuum of early discovery, including:
- Molecular biology (cloning, gene expression analysis, protein expression, genomic engineering)
- AI-enhanced target identification and wet-lab validation
- Assay development (cellular and biochemical)
- Compound management
- Fully automated high-throughput screening, with diverse readouts including electrophysiology, quantitative gene expression, and high-content imaging
- Virtual screening
- Hit characterization and profiling
- Access to Axxam’s physical compound collections (universal and focused) and virtual libraries
- Hit-to-lead optimization
- Early in vitro assessment of efficacy, biodistribution, and toxicity, including New Approach Methodologies (NAMs)