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How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

Most Americans drink less juice than guidelines allow, study finds

A new study of NHANES 2017–2023 data shows that most Americans drink far less 100% fruit juice than the Dietary Guidelines allow. Juice consumption was linked to better diet quality, higher nutrient intake, and did not displace whole fruit.

24 Aug 2025

Study shows brain keeps internal body map intact after amputation

Researchers tracked brain activity before and after arm amputation and found that hand and lip maps in the cortex remained remarkably stable for up to five years. This challenges decades-old assumptions of large-scale remapping and supports the idea of a resilient internal body model.

24 Aug 2025

A 9-point checklist to improve AI-based image analysis in pathology

A new article in Veterinary Pathology introduces a 9-point checklist designed to improve the reporting quality of studies that use artificial intelligence (AI)-based automated image analysis (AIA). As AI tools become more widely used in pathology-based research, concerns have emerged about the reproducibility and transparency of published findings.

23 Aug 2025

iconPCR™: Powering the next wave of metagenomics and microbiome discovery

The landscape of metagenomics and microbiome research is evolving at breakneck speed. As sequencing technologies improve and the demand for high-resolution, bias-free microbial data grows, the bottleneck is shifting from sequencing itself to the quality of upstream sample preparation.

From n6 23 Aug 2025

Next-gen sequencing reveals the regulatory potential of the non-coding genome

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.

23 Aug 2025

n6™ announces strategic partnership with SeqCenter to deliver unmatched data quality in metagenomics

n6 is proud to announce a strategic partnership with SeqCenter, who is launching a groundbreaking full-length 16S sequencing service at FEMS Micro.

From n6 23 Aug 2025

n6 expands European presence to empower scientists and simplify NGS workflows

n6, the award-winning innovator in next-generation sequencing (NGS) workflow solutions, is proud to announce a major expansion of its European enablement efforts.

From n6 23 Aug 2025

WHO and WMO report highlights extreme heat's impact on workers

The World Health Organization (WHO) and the World Meteorological Organization (WMO) have published a new joint report and guidance highlighting the growing global health challenges posed by extreme heat on workers.

23 Aug 2025

Inconsistent state laws undermine sexual education across the United States

While the majority of states require public school students to take at least one sexual education course, a patchwork of state-level provisions that mandate inaccurate, outdated, or politically motivated curricula may inhibit students from receiving essential information for their sexual health and well-being.

22 Aug 2025

SOX2 drives progression and therapy resistance in advanced prostate cancer

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men.

22 Aug 2025

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions.

22 Aug 2025

Study finds major health burden from oil and gas pollution across the United States

Air pollution from oil and gas is causing 91,000 premature deaths and hundreds of thousands of health issues across the United States annually, with Black, Asian, Native American and Hispanic groups consistently the most affected, finds a major new study led by researchers at UCL and the Stockholm Environment Institute (SEI).

22 Aug 2025

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs).

22 Aug 2025

Working-age adults with disabilities face much higher rates of loneliness

Working-age adults with disabilities experience far higher rates of loneliness than those without, according to a new study from researchers at the Brown University School of Public Health and the Warren Alpert Medical School.

22 Aug 2025

Skin color may influence phototherapy effectiveness in newborns with jaundice

Jaundice is one of the most common medical issues in newborns, affecting nearly 80 percent of full-term infants in their first days of life.

22 Aug 2025

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future.

22 Aug 2025

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

In rapidly aging societies like Japan, the simple act of swallowing meals can be challenging for many. This condition, known as dysphagia, affects millions of people worldwide and can significantly deteriorate a person's quality of life.

22 Aug 2025

Urban heat and pollution linked to behavioral changes in children

Individuals living in urban cities are experiencing the combined effect of increasing temperatures and poor air quality, often referred to as the urban heat dome.

22 Aug 2025

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Researchers from Kyoto Prefectural University of Medicine and collaborating Japanese institutions found that patients carrying colibactin-producing Escherichia coli (pks+ E. coli) in their colon polyps were more than three times as likely to have a history of colorectal cancer compared to those without the bacterium.

22 Aug 2025

Medical News

How a single gene reshapes pain perception through polyamine signaling

Most Americans drink less juice than guidelines allow, study finds

Study shows brain keeps internal body map intact after amputation

A 9-point checklist to improve AI-based image analysis in pathology

iconPCR™: Powering the next wave of metagenomics and microbiome discovery

Next-gen sequencing reveals the regulatory potential of the non-coding genome

n6™ announces strategic partnership with SeqCenter to deliver unmatched data quality in metagenomics

n6 expands European presence to empower scientists and simplify NGS workflows

WHO and WMO report highlights extreme heat's impact on workers

Inconsistent state laws undermine sexual education across the United States

SOX2 drives progression and therapy resistance in advanced prostate cancer

CHI3L1 emerges as a powerful biomarker for liver disease diagnosis and management

Study finds major health burden from oil and gas pollution across the United States

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

Working-age adults with disabilities face much higher rates of loneliness

Skin color may influence phototherapy effectiveness in newborns with jaundice

Researchers identify molecular mechanism behind tamoxifen-related uterine cancer

New 3D bioprinting method can customize protein-based emulsion gels for dysphagia diets

Urban heat and pollution linked to behavioral changes in children

Carriers of colibactin-producing E. coli face threefold increase in colorectal cancer risk

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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