Metabolism News and Research

Latest Metabolism News and Research

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

A Montr-al research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in today's printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk.

15 Jan 2014

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

The presence of a gene variant in people with mild cognitive impairment is associated with accelerated rates of brain atrophy, according to a new study published online in the journal Radiology.

15 Jan 2014

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine.

13 Jan 2014

Researchers explore possible effects that diet have on gene expression through epigenetic mechanisms

In "Epigenetics: A New Link Between Nutrition and Cancer", a recent article from Nutrition and Cancer: An International Journal, a publication of Routledge, researchers explore the possible effects that diet can have on gene expression through epigenetic mechanisms.

13 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Researchers at Joslin Diabetes Center have discovered that a hormone long associated with weight loss and improved glucose metabolism is linked to activation of calorie-burning brown fat.

10 Jan 2014

Research: SLPI protein produced by body in response to injury plays vital role in patients with ALF

Findings published in the American Association for the Study of Liver Diseases journal, Hepatology, indicate that infection, the commonest cause of mortality in patients with acute liver failure, may be decreased by inhibiting the activity of a protein found in saliva called SLPI.

10 Jan 2014

Minority patients and those of lower socioeconomic status are more likely to have advanced thyroid cancer

UCLA researchers have found that minority patients and those of lower socioeconomic status are far more likely to have advanced thyroid cancer when they are diagnosed with the disease than white patients and those in higher economic brackets.

10 Jan 2014

Brown University biochemist targets diabetes

People with type 2 diabetes can make insulin but their bodies use it so poorly that glucose levels run amok. It's been difficult for scientists to understand what's going awry in the way that tiny, fast-moving proteins signal and regulate glucose metabolism. As a result, while drugs can help somewhat, many patients still must monitor their glucose and inject insulin.

10 Jan 2014

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Gastric bypass surgery is a type of bariatric operation that results in weight loss and stimulates metabolic effects that treat diabetes and other cardiovascular risk factors such as diabetes, high cholesterol, and hypertension.

9 Jan 2014

UCSB psychology professor finds that weight-stigmatizing messages may have the opposite effect

If you're one of the millions of people who count losing weight among their top New Year's resolutions, you might want to pay careful attention to some new findings by UC Santa Barbara psychology professor Brenda Major.

9 Jan 2014

UMMS assistant professor recognized with Presidential Early Career Award for Scientists and Engineers

University of Massachusetts Medical School Assistant Professor Thomas G. Fazzio, PhD, was recognized as a rising scientific star by President Obama with a Presidential Early Career Award for Scientists and Engineers.

9 Jan 2014

Researchers use stem cells to study bone disorders from patients afflicted with genetic bone disease

Researchers have developed a new way to study bone disorders and bone growth, using stem cells from patients afflicted with a rare, genetic bone disease.

9 Jan 2014

Scientists believe that new links between brain cells help encode new memories and skills

In adults, some brain regions retain a "childlike" ability to establish new connections, potentially contributing to our ability to learn new skills and form new memories as we age, according to new research from Washington University School of Medicine in St. Louis and the Allen Institute for Brain Science in Seattle.

8 Jan 2014

AP-1 proteins modulate fat accumulation in liver, say researchers

Excessive alcohol consumption, as well as obesity leads to the accumulation of fat in the liver, a disease termed fatty liver disease (FLD) or steatosis. FLD is one of the most prevalent diseases in Western societies and affects about 30% of the adult population. Importantly, FLD increases the risk of liver failure, diabetes and cancer and no pharmacological therapies exist for this detrimental disease.

8 Jan 2014

Research reveals two new genetic causes of neonatal diabetes

Research by the University of Exeter Medical School has revealed two new genetic causes of neonatal diabetes.

8 Jan 2014

Study sheds light on the biological underpinnings of obesity

A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study, published in the January 8 issue of the Journal of Neuroscience, reveals how a protein in the brain helps regulate food intake and body weight. The findings reveal a potential new avenue for the treatment of obesity and may help explain why medications that are prescribed for epilepsy and other conditions that interfere with this protein, such as gabapentin and pregabalin, can cause weight gain.

7 Jan 2014

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Although brain growth slows as individuals age, some regions of the brain continue to develop for longer than others, creating new connections and remodeling existing circuitry.

7 Jan 2014

FDA accepts NPS Pharmaceuticals' Natpara BLA for review

NPS Pharmaceuticals, Inc., a global biopharmaceutical company pioneering and delivering therapies that transform the lives of patients with rare diseases worldwide, today announced that the U.S. Food and Drug Administration has accepted and filed for review the company's Biologics License Application for Natpara (recombinant human parathyroid hormone 1-84, (rhPTH[1-84])) for the treatment of hypoparathyroidism.

7 Jan 2014

Amneal launches generic Esomeprazole strontium delayed-release capsules 49.3 mg

Amneal Pharmaceuticals LLC today announced the launch of generic Esomeprazole strontium delayed-release capsules 49.3 mg. This new esomeprazole therapy is the generic equivalent of the recently launched brand Esomeprazole strontium. It contains the same active moiety (esomeprazole) in a different salt form as found in the leading PPI brand Nexium (esomeprazole magnesium) and presents a potentially more affordable treatment option for GERD in adult patients.

6 Jan 2014

Metabolism News and Research

Latest Metabolism News and Research

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

Presence of gene variant in people with MCI associated with accelerated rates of brain atrophy

MRI method to map creatine in heart may help detect disorders earlier than traditional methods

Researchers explore possible effects that diet have on gene expression through epigenetic mechanisms

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Hormone associated with improved glucose metabolism activates calorie-burning brown fat

Research: SLPI protein produced by body in response to injury plays vital role in patients with ALF

Minority patients and those of lower socioeconomic status are more likely to have advanced thyroid cancer

Brown University biochemist targets diabetes

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

UCSB psychology professor finds that weight-stigmatizing messages may have the opposite effect

UMMS assistant professor recognized with Presidential Early Career Award for Scientists and Engineers

Researchers use stem cells to study bone disorders from patients afflicted with genetic bone disease

Scientists believe that new links between brain cells help encode new memories and skills

AP-1 proteins modulate fat accumulation in liver, say researchers

Research reveals two new genetic causes of neonatal diabetes

Study sheds light on the biological underpinnings of obesity

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

FDA accepts NPS Pharmaceuticals' Natpara BLA for review

Amneal launches generic Esomeprazole strontium delayed-release capsules 49.3 mg

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production