Hepatitis B News and Research

Latest Hepatitis B News and Research

New mouse model faithfully mimics brain damage caused by severe Rift Valley Fever virus infection

A new mouse model identified by virologists from the University of Pittsburgh might revolutionize development of therapies targeting brain inflammation caused by Rift Valley Fever virus (RVFV).

15 Jul 2022

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

Researchers have created a liquid biopsy test, which uses two circulating proteins, to test for major liver diseases.

14 Jul 2022

SARS-CoV-2 surrogates can survive on refrigerated or frozen meat products for up to 30 days, study finds

SARS-CoV-2 surrogates can survive on meat products in the refrigerator or the freezer, for up to 30 days. Those findings are published in Applied and Environmental Microbiology, a journal of the American Society for Microbiology.

11 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

New method helps determine alcohol consumption in fatty liver disease

It is important to know whether patients have non-alcoholic fatty liver disease (NAFLD) or alcohol-related liver disease (ALD), as this distinction plays a key role in treatment and prognosis but cannot be reliably determined by established diagnostic means.

5 Jul 2022

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases.

4 Jul 2022

Impact of SARS-CoV-2 infection on menstrual cycle

Researchers systematically reviewed the impact of COVID-19 on the menstrual cycle.

4 Jul 2022

Machine-learning algorithms can help distinguish acute cholangitis and alcohol-associated hepatitis

Acute cholangitis is a potentially life-threatening bacterial infection that often is associated with gallstones. Symptoms include fever, jaundice, right upper quadrant pain, and elevated liver enzymes.

1 Jul 2022

Crystal structure of a human endogenous reverse transcriptase revealed

The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according to a study co-authored by a Rutgers researcher.

30 Jun 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

CDC data shows a sharp decrease in HIV testing during first year of COVID-19 pandemic

New CDC data published ahead of National HIV Testing Day (Monday, June 27) show a sharp decrease in the number of CDC-funded HIV tests administered in health care and non-health-care settings (43% and 50%, respectively) from 2019 to 2020, the first year of the COVID-19 pandemic.

28 Jun 2022

New tissue model helps trace the steps involved in liver regeneration

The human liver has amazing regeneration capabilities: Even if up to 70 percent of it is removed, the remaining tissue can regrow a full-sized liver within months.

27 Jun 2022

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Rensselaer Polytechnic Institute researchers Gaetano Montelione and Christopher Cioffi will use a five-year, $3.5 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to develop a low-dose, oral COVID antiviral drug that can be administered at home.

27 Jun 2022

Chemically modified rocaglates have a stronger effect against viral replication

Hepatitis E virus (HEV) is widespread, and so far there is no effective drug. In the search for one, the so-called rocaglates have come into focus: plant compounds that can inhibit the replication of viruses.

27 Jun 2022

Simple blood test can predict liver cancer risk in NAFLD patients

An estimated one-quarter of adults in the U.S. have nonalcoholic fatty liver disease (NAFLD), an excess of fat in liver cells that can cause chronic inflammation and liver damage, increasing the risk of liver cancer.

22 Jun 2022

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease.

21 Jun 2022

UB program secures $12.8 million to improve the quality of global HIV research

The National Institutes of Health (NIH) has awarded $12.8 million to the University at Buffalo School of Pharmacy and Pharmaceutical Sciences to lead a clinical pharmacology quality assurance program for NIH-funded laboratories and research networks across the globe conducting HIV and infectious disease research.

16 Jun 2022

Obesity causes COVID vaccines to lose their efficacy more rapidly

In a recent study posted to the medRxiv* pre-print server, researchers examined a clinical cohort of severely obese people vaccinated with coronavirus disease 2019 (COVID-19) vaccines to determine the relationship between an individual's body mass index (BMI) and COVID-19-related hospitalization and mortality.

16 Jun 2022

Will the US overcome its covid complacency even as the threat returns?

A few months ago, it seemed as though the country was poised to finally tame the pandemic, after two years of restrictions and tens of billions in government spending.

15 Jun 2022

Study shows alarming trends in mortality from alcoholic cirrhosis in the U.S.

Alcoholic cirrhosis is an advanced form of alcohol-related liver disease. In the United States between 2010 and 2016, alcohol-related liver disease was the primary cause of nearly 1 in 3 liver transplants, surpassing hepatitis C.

14 Jun 2022

Hepatitis B News and Research

Latest Hepatitis B News and Research

New mouse model faithfully mimics brain damage caused by severe Rift Valley Fever virus infection

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

SARS-CoV-2 surrogates can survive on refrigerated or frozen meat products for up to 30 days, study finds

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

New method helps determine alcohol consumption in fatty liver disease

Scientists discover how a protein and enzymes interact to allow hepatitis A virus replication

Impact of SARS-CoV-2 infection on menstrual cycle

Machine-learning algorithms can help distinguish acute cholangitis and alcohol-associated hepatitis

Crystal structure of a human endogenous reverse transcriptase revealed

Investigating the prerequisites for developing RNA-based antibiotics

CDC data shows a sharp decrease in HIV testing during first year of COVID-19 pandemic

New tissue model helps trace the steps involved in liver regeneration

Rensselaer scientists secure $3.5 million grant to develop a low-dose, oral COVID antiviral drug

Chemically modified rocaglates have a stronger effect against viral replication

Simple blood test can predict liver cancer risk in NAFLD patients

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

UB program secures $12.8 million to improve the quality of global HIV research

Obesity causes COVID vaccines to lose their efficacy more rapidly

Will the US overcome its covid complacency even as the threat returns?

Study shows alarming trends in mortality from alcoholic cirrhosis in the U.S.

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Hepatitis B News and Research

Latest Hepatitis B News and Research

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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