Gene News and Research

Latest Gene News and Research

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

CRISPR off-switch discovered: Safer gene editing for future therapies

Using CRISPR, an immune system bacteria use to protect themselves from viruses, scientists have harnessed the power to edit genetic information within cells.

19 Jan 2024

Unveiling the cellular mechanisms of engram consolidation and memory refinement

Think of a time when you had two different but similar experiences in a short period. Maybe you attended two holiday parties in the same week or gave two presentations at work.

19 Jan 2024

New discovery sheds light on the genetic basis of a rare skeletal disorder

A McGill-led team of researchers have made an important discovery shedding light on the genetic basis of a rare skeletal disorder.

19 Jan 2024

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers compared SARS-CoV-2 Omicron variant of concern replication in human cell lines and primary airway cultures and measured host responses to infection.

19 Jan 2024

Researchers make new breakthrough in better understanding the immune system to fight diseases

The Xue Lab at the Hackensack Meridian Center for Discovery and Innovation (CDI) has made another breakthrough in better understanding, and potentially modulating, the immune system to fight diseases.

18 Jan 2024

Wireless magnetogenetic approach could be used to treat motor dysfunction in people with Parkinson’s disease

Electrical deep brain stimulation (DBS) is a well-established method for treating disordered movement in Parkinson's disease.

18 Jan 2024

Machine learning algorithm decodes mutations driving cancer treatment resistance

In a groundbreaking study published on January 18, 2024, in Cancer Discovery, scientists at University of California San Diego School of Medicine leveraged a machine learning algorithm to tackle one of the biggest challenges facing cancer researchers: predicting when cancer will resist chemotherapy.

18 Jan 2024

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells.

18 Jan 2024

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Researchers investigate the mechanism responsible for amphotericin B tolerance of Cryptococcus neoformans.

18 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

ALS progression linked to mitochondria-associated membrane-ER disconnection

Researchers at Nagoya University in Japan have discovered a relationship between the progression of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the disruption of mitochondria-associated membranes (MAM), the contact point between the mitochondria and the endoplasmic reticulum (ER) of the cell.

17 Jan 2024

23% of dementia cases linked to controllable risk factors vary by race and ethnicity

Approximately 23% of people diagnosed with Alzheimer's disease or another related dementia in their 60s and later have cases that can be explained by controllable risk factors such as high blood pressure, diabetes, physical inactivity, and too little or too much sleep, and that percentage varies depending on race and ethnicity, according to a new study published in the January 17, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

17 Jan 2024

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Bacterial infections can lead to the formation of abscesses - pockets of dead cells and debris surrounded by inflammatory immune cells. Bacteria multiply within abscesses, causing more inflammation and further damage to surrounding tissues.

17 Jan 2024

Decoding blood cancer secrets to optimize CAR T therapy

Chimeric antigen receptor T-cell therapy, or CAR T, has dramatically improved the treatment of certain blood cancers. Initially approved for patients who had failed multiple lines of therapy, clinical trials have shown CAR T can be used as an earlier treatment option.

17 Jan 2024

Gene News and Research

Latest Gene News and Research

Ludwig scientists deconstruct the blood supply of brain metastases

CRISPR off-switch discovered: Safer gene editing for future therapies

Unveiling the cellular mechanisms of engram consolidation and memory refinement

New discovery sheds light on the genetic basis of a rare skeletal disorder

Study shows Omicron variants evade immune system like predecessors, suggesting key evolutionary trait in SARS-CoV-2

Researchers make new breakthrough in better understanding the immune system to fight diseases

Wireless magnetogenetic approach could be used to treat motor dysfunction in people with Parkinson’s disease

Machine learning algorithm decodes mutations driving cancer treatment resistance

Short strands of toxic RNAs contribute to brain cell death and DNA damage in Alzheimer's

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

ALS progression linked to mitochondria-associated membrane-ER disconnection

23% of dementia cases linked to controllable risk factors vary by race and ethnicity

Anti-HIV drugs can be used to prevent inflammatory complications of bacterial sepsis

Decoding blood cancer secrets to optimize CAR T therapy

Study suggests gut phages may be involved in the development of asthma

Study shows promise of gene-based screening to fight colorectal cancer

Researchers uncover the role of inherited genetic variants in rare type of blood cancer

Unlocking the anti-inflammatory secrets of bergamot byproducts

Review of traditional treatments and novel nutritional interventions for sickle cell disease

Genomics - Industry Focus eBook (2nd edition) eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson