Gene News and Research

Latest Gene News and Research

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Advancing therapeutic insights: The impact of understanding cellular target engagement with NanoBRET® technology

In this Interview, NewsMedical speaks with Amy Landreman about NanoBRET® Technology and its role in cellular target engagement.

From Promega Corporation 30 May 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

New weapon against cancer: "DNA warhead" targets mutant protein in tumor cells

Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body's ability to fight tumors and even encouraging their growth.

29 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Heart-healthy habits keep you biologically young, study shows

A new study in the Journal of the American Heart Association reveals that heart-healthy lifestyle factors are linked to younger biological age and lower cardiovascular disease risk through DNA methylation.

29 May 2024

Opioid receptors play unexpected role in gut nervous system development

Researchers at Rice University have revealed a previously unknown function of opioid receptors in the development of the enteric nervous system (ENS), often referred to as the "brain in the gut."

29 May 2024

Foam-based delivery system could revolutionize gene therapies

Foam mixed with medications is already used to treat conditions such as varicose veins, hemorrhoids, wounds on the skin and even hair loss.

29 May 2024

Researchers decode spatial structure of prime editor

Joint research led by Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo determined the spatial structure of various processes of a novel gene-editing tool called "prime editor."

29 May 2024

New research highlights a promising approach to tackling for ALS

A recent collaborative research endeavor, published in the prestigious Cell Press journal Cell Reports Medicine, highlights a promising therapeutic avenue for amyotrophic lateral sclerosis (ALS).

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

In contemporary society, obesity has emerged as a worldwide chronic metabolic disorder, imposing substantial burdens on both individual health and healthcare systems.

29 May 2024

Study links low oxytocin levels to symptoms of polycystic ovary syndrome

The role of oxytocin (OT) in polycystic ovary syndrome (PCOS).

29 May 2024

Heart healthy behaviors may slow biological aging, research shows

The benefit of better heart health may be associated with the positive impact of heart healthy lifestyle factors on biological aging (the age of the body and its cells), according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 May 2024

Cellular Origins and Cell and Gene Therapy Catapult collaborate to demonstrate universal automation of CGT manufacturing

Cellular Origins, a TTP Company focused on enabling scalable, cost-effective, and efficient manufacture of cell and gene therapies (CGTs), and the Cell and Gene Therapy Catapult (CGT Catapult), an independent innovation and technology organisation specializing in the advancement of the cell and gene therapy industry, today announced a collaboration to demonstrate universal automation of CGT manufacturing.

29 May 2024

Why use light scattering to analyze proteins and viral vectors?

In this interview, Dr. Michelle Chen, Senior Director of Analytical Sciences at Wyatt Technology, talks to NewsMedical about how to use light scattering techniques to analyze proteins for their multi-attribute quantification (MAQ).

From Waters | Wyatt Technology 29 May 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

MUSC researchers unravel the mystery of cancer recurrence

MUSC Hollings Cancer Center researchers have unlocked a discovery that could help to explain why cancer can recur in patients who have undergone chemotherapy or radiotherapy.

28 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024