Gene News and Research

Latest Gene News and Research

Expanding genetic Horizons: GWAS insights from the VA Million Veterans Program

A large-scale genome-wide association study (GWAS) using data from the United States Department of Veterans Affairs (VA) Million Veterans Program (MVP) – one of the largest US-based biobanks – fills crucial gaps in our knowledge of the relationships between genes, traits, and disease across diverse populations, according to a new study.

19 Jul 2024

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product.

19 Jul 2024

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Xueqing Hu , Ujjwol Khatri , Tao Shen , and Jie Wu, at University of Oklahoma Health Sciences Center, USA, provides a comprehensive review of the role of the RET (REarranged during Transfection) receptor tyrosine kinase in cancer development and the advancements in RET-targeted cancer therapies.

19 Jul 2024

Ginseng genome unlocks secrets of medicinal benefits

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine. This pivotal discovery promises to drive forward breeding initiatives and augment the plant's medicinal qualities, unlocking new possibilities for therapeutic applications.

19 Jul 2024

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Blocking IL-11 signaling extends lifespan and healthspan in mice, reducing age-related metabolic decline, frailty, and cancer incidence.

18 Jul 2024

Study uncovers how OTX2 drives aggressive childhood brain cancer

In a report published in Nature Cell Biology, researchers at Baylor College of Medicine, Texas Children's Hospital, the University of Manitoba and collaborating institutions revealed an unexpected way in which the protein OTX2 drives the progression of medulloblastoma – the most common aggressive childhood brain cancer.

18 Jul 2024

Blocking IL-11 protein extends lifespan and health in mice by 25%, study shows

Scientists at the Medical Research Council Laboratory of Medical Science and Imperial College London have discovered that 'switching off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%.

18 Jul 2024

Common blood thinner can be repurposed as an inexpensive antidote for cobra venom

Scientists at the University of Sydney and Liverpool School of Tropical Medicine have made a remarkable discovery: a commonly used blood thinner, heparin, can be repurposed as an inexpensive antidote for cobra venom.

18 Jul 2024

Distinct signaling pathway drives the transformation of epithelial cells into aggressive tumors

A distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells.

18 Jul 2024

Breakthrough gene therapy offers hope for Duchenne muscular dystrophy

A new gene therapy treatment for Duchenne muscular dystrophy shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles.

18 Jul 2024

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

Researchers compared the distribution of sialic acid receptors in the respiratory tract and mammary glands of dairy cattle naturally infected with the highly pathogenic avian influenza A(H5N1) virus.

18 Jul 2024

CU Boulder research uncovers role of endogenous retroviruses in cancer

Peek inside the human genome and, among the 20,000 or so genes that serve as building blocks of life, you'll also find flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago.

18 Jul 2024

Study links circadian rhythm disruption to obesity and diabetes

Disruption of circadian rhythms and clock gene expression is linked to adverse metabolic health outcomes, including obesity and diabetes. Further research is needed to understand these relationships and their implications for treatment and prevention.

17 Jul 2024

Increased exposure to residential greenery may help stave off cognitive decline

A new study found that increased exposure to residential greenery may help stave off cognitive decline by an annual rate of eight months.

17 Jul 2024

Researchers find a special group of "first responder" cells crucial for triggering blood sugar response

How does our body control blood sugar so precisely? An international research team led by scientists from the Paul Langerhans Institute Dresden (PLID) of the German Center for Diabetes Research brought us a step closer to the answer.

17 Jul 2024

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

An international study has discovered that people living with the neurodegenerative condition Spinal Muscular Atrophy (SMA) are at higher risk of developing fatty liver disease, suggesting that SMA patients may face additional health problems over time.

17 Jul 2024

Study highlights the role of RGS16 in glioma progression

Gang Li et al., at Department of Neurosurgery, Qilu Hospital, Shandong University, China, presented a comprehensive study on the role of regulator of G-protein signaling 16 (RGS16) in the progression of glioma, a highly aggressive central nervous system tumor.

17 Jul 2024

Novel method enables RNA detection with Cas12 nucleases

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

Harnessing cell's natural delivery system for targeted drug delivery

Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs - molecules like proteins, RNA and combinations of the two - to specific diseased parts of the body.

17 Jul 2024

UCLA investigators receive $800,000 grant to treat and prevent aggressive kidney cancer

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have received an $800,000 grant from the V Foundation to find new ways to treat and prevent a severe form of kidney cancer associated with a hereditary syndrome caused by mutations in the fumarate hydratase (FH) gene.

16 Jul 2024

Gene News and Research

Latest Gene News and Research

Expanding genetic Horizons: GWAS insights from the VA Million Veterans Program

Modulating T-cell response: Innovations in AAV8 gene therapy for retinal diseases

Deciphering the role of RET in cancer and breakthroughs in targeted treatments

Ginseng genome unlocks secrets of medicinal benefits

Breakthrough in aging research: Blocking IL-11 extends lifespan and improves health in mice

Study uncovers how OTX2 drives aggressive childhood brain cancer

Blocking IL-11 protein extends lifespan and health in mice by 25%, study shows

Common blood thinner can be repurposed as an inexpensive antidote for cobra venom

Distinct signaling pathway drives the transformation of epithelial cells into aggressive tumors

Breakthrough gene therapy offers hope for Duchenne muscular dystrophy

Study finds dairy cows vulnerable to flu strains from birds, humans, and pigs

CU Boulder research uncovers role of endogenous retroviruses in cancer

Study links circadian rhythm disruption to obesity and diabetes

Increased exposure to residential greenery may help stave off cognitive decline

Researchers find a special group of "first responder" cells crucial for triggering blood sugar response

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

Study highlights the role of RGS16 in glioma progression

Novel method enables RNA detection with Cas12 nucleases

Harnessing cell's natural delivery system for targeted drug delivery

UCLA investigators receive $800,000 grant to treat and prevent aggressive kidney cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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