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Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections.

2 Apr 2016

Research suggests ibuprofen does not increase bleeding risk after plastic surgery

Patients are often instructed not to take ibuprofen and other nonsteroidal anti-inflammatory drugs before or after surgery because of increased bleeding risk. But available evidence suggests that ibuprofen does not increase the risk of bleeding after plastic surgery procedures, according to a research review in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

2 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

GHIT Fund invests in two innovative malaria eradication tools

The Global Health Innovative Technology Fund (GHIT Fund) announced today that it’s investing US$1,383,785 in a pair of innovative malaria eradication tools—a vaccine that could block transmission of two species of the deadly disease and a rapid field test that can reveal a malaria infection in minutes.

1 Apr 2016

Experimental Ebola vaccine may help fight latest flare-up in Guinea

Hundreds of people who may have been in contact with 8 individuals infected with Ebola virus in Guinea’s southern prefectures of Nzérékoré and Macenta have been vaccinated with the experimental Ebola vaccine in a bid to contain the latest flare-up of Ebola.

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Researchers at the University of Pittsburgh School of Medicine and Arts & Sciences have designed a more effective version of an FDA-approved epilepsy drug with the potential for fewer side effects, according to a study published on March 22 in Molecular Pharmacology. The experimental agent also could prove to be a treatment for tinnitus and other disorders caused by volatile neural signaling.

31 Mar 2016

Two recently discovered compounds show promise for treating Ewing sarcoma in children

Two recently discovered compounds have shown promise in preclinical studies for treating Ewing sarcoma, a rare cancer that predominantly affects children and adolescents.

31 Mar 2016

Psychedelic compounds could treat patients with mental health issues

Psychedelic compounds have had a colorful past. Although initially investigated for medical uses, they were banned after cultural and political times changed in the 1960s and 1970s. Now, the compounds are getting another chance in the mainstream, according to the cover story of Chemical & Engineering News, the weekly news magazine of the American Chemical Society.

31 Mar 2016

Four commonly used medications to treat pregnant women with migraines may not be safe

According to doctors at Wake Forest Baptist Medical Center, medications and treatments long considered safe to treat pregnant women with migraines may not be.

31 Mar 2016

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Key opinions leaders in the field of haematopoetic stem cell transplantation (HSCT) will address the role of Cyclophosphamide, an anti-cancer chemotherapy drug, during the 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT) that will welcome more than 4,500 delegates in the host city of Valencia, Spain from the 3rd to the 6th of April 2016.

31 Mar 2016

Opioids could be dangerous, deadly at high doses

Most people know that heroin is a dangerous drug, but its cousins, the legal, pharmaceutical opioids, such as codeine or hydrocodone, must be safe, right?Not so fast.Opioids—which include the illegal drug heroin as well as prescription medications, including hydrocodone (such as Vicodin), oxycodone (such as OxyContin and Percocet), morphine and codeine—can be dangerous, even deadly, at high doses.

31 Mar 2016

NHS England to provide crucial funding for Janssen's HIV treatment, REZOLSTA

Janssen-Cilag Ltd today announced that NHS England will provide crucial funding for its once-daily, fixed-dose combination of darunavir and the pharmacoenhancer, cobicistat, called REZOLSTA.

31 Mar 2016

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

Bio Products Laboratory, Limited (BPL) today announced that the European Medicines Agency has granted marketing authorisation for Coagadex.

31 Mar 2016

Certain types of hormonal contraceptives may increase risk of seizures in women with epilepsy

Could certain types of hormonal contraceptives cause an increase in seizures in women with epilepsy? A recent Texas A&M Health Science Center study suggests that ethinyl estradiol, the primary component of oral contraceptives, could be detrimental to the epileptic brain.

30 Mar 2016

Beaumont urologists study use of enobosarm to treat women's SUI

Could a one-a-day pill be the answer for women with stress urinary incontinence - a condition resulting in leakage with coughing, sneezing and laughing?

30 Mar 2016

Optimized approach for determining prescribed medication associations within pharmacy environment

Researchers at Binghamton University and pharmacy solutions provider Innovation Associates have developed an optimized approach for determining prescribed medication associations within a high-volume pharmacy environment that could save money and time.

30 Mar 2016

Multiple combination therapies could prevent malaria resistance

In order to preserve first-line drugs for treating malaria, multiple combination therapies should be deployed within a population to prevent resistance from developing, according to Maciej Boni from the Centre for Tropical Medicine and Global Health, University of Oxford, UK, and colleagues in a Policy Forum article published in this week's PLOS Medicine.

30 Mar 2016

UGA and Sanofi Pasteur researchers develop new H1N1 influenza vaccine

Researchers at the University of Georgia and Sanofi Pasteur, the vaccines division of Sanofi, announced today the development of a vaccine that protects against multiple strains of both seasonal and pandemic H1N1 influenza in mouse models.

30 Mar 2016

High out-of-pocket costs linked to lower use of specialty drugs

"Specialty drugs" have become important treatment options for many serious and chronic diseases, and in some conditions like cancer they represent the only chance for long-term survival.

29 Mar 2016

Pharmaceutical News

Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

Research suggests ibuprofen does not increase bleeding risk after plastic surgery

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

GHIT Fund invests in two innovative malaria eradication tools

Experimental Ebola vaccine may help fight latest flare-up in Guinea

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Two recently discovered compounds show promise for treating Ewing sarcoma in children

Psychedelic compounds could treat patients with mental health issues

Four commonly used medications to treat pregnant women with migraines may not be safe

Key opinions leaders to discuss role of cyclophosphamide in the field of HSCT

Opioids could be dangerous, deadly at high doses

NHS England to provide crucial funding for Janssen's HIV treatment, REZOLSTA

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

Certain types of hormonal contraceptives may increase risk of seizures in women with epilepsy

Beaumont urologists study use of enobosarm to treat women's SUI

Optimized approach for determining prescribed medication associations within pharmacy environment

Multiple combination therapies could prevent malaria resistance

UGA and Sanofi Pasteur researchers develop new H1N1 influenza vaccine

High out-of-pocket costs linked to lower use of specialty drugs

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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