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Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

UW researchers find similarities between diabetes and Alzheimer's protein clusters

Of the 38 million Americans who have diabetes at least 90% have Type 2, according to the Centers for Disease Control and Prevention.

29 Feb 2024

Newly identified Enterococcus species shed light on antibiotic resistance spread

Antibiotic-resistant infection is projected to catch up to cancer as the leading cause of death by 2050, making understanding and limiting the spread of antibiotic-resistant bacteria a priority worldwide.

29 Feb 2024

Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows

A University of Kansas study of rare gene mutations that cause hereditary Alzheimer's disease shows these mutations disrupt production of a small sticky protein called amyloid.

29 Feb 2024

Corticosteroids may restore sense of smell in COVID-19 patients

COVID-19 is known to cause loss of smell in certain patients. While this symptom is generally temporary, approximately 10% of patients may suffer from it for 6 months or more.

29 Feb 2024

Interdisciplinary project aims to decode human kinome in brain function and disease

The Chan Zuckerberg Initiative (CZI) announced four multi-year Exploratory Cell Networks grants for researchers exploring the frontiers of genomics, cell biology, and synthetic biology by developing new measurement technologies.

29 Feb 2024

Research uncovers key therapeutic target for reversing accelerated atherosclerosis in diabetes

Diabetes accelerates the development of atherosclerosis, increasing the incidence of cardiovascular events.

29 Feb 2024

Exercise, GLP-1 receptor agonist, or combined approach explored in year-long study

Researchers compare the extent of weight loss after one-year termination of active intervention with GLP-1 receptor agonist, exercise, or combination.

29 Feb 2024

Association of estrogen-containing menopause hormonal therapy with COVID-19 mortality

Researchers evaluated coronavirus disease 2019 (COVID-19)-related mortality among perimenopausal women.

29 Feb 2024

Research finds link between unhealthy eating and chronic pain severity, calls for comprehensive dietary support

Dietary and lifestyle habits among individuals living with chronic pain.

29 Feb 2024

Research finds link between unhealthy eating and chronic pain severity, calls for comprehensive dietary support

Dietary and lifestyle habits among individuals living with chronic pain.

29 Feb 2024

Is posttraumatic epilepsy associated with long-term dementia risk?

The associations between post-traumatic epilepsy (PTE) and the risk of dementia.

29 Feb 2024

NIH funds study on neural mechanisms behind autism and sound sensitivity

Supported by a $2 million R01 grant from the National Institutes of Health, the Auerbach Lab at the Beckman Institute for Advanced Science and Technology will examine how different genes associated with autism spectrum disorders may similarly impact our brain's neurons, resulting in heightened sensitivity to sounds.

28 Feb 2024

Sensory cues from the opposite sex affect aging in animals

Sensory cues from the opposite sex can influence how animals age, a University of Otago-led study has found.

28 Feb 2024

Study demonstrates the deleterious effects of chronic cocaine use on functional brain networks

A collaborative research endeavor by scientists in the Departments of Radiology, Neurology, and Psychology and Neuroscience at the UNC School of Medicine have demonstrated the deleterious effects of chronic cocaine use on the functional networks in the brain.

28 Feb 2024

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

A new research paper was published in Oncotarget's Volume 15 on February 22, 2024, entitled, "Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health."

28 Feb 2024

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

Scientists at EPFL uncover the mechanism by which cells mark the protein cGAS for degradation, which is critical in preventing the immune system from mistakenly attacking the body's own tissues.

28 Feb 2024

UB research may offer a more streamlined approach to developing cancer drugs

Drug discovery can be a frustrating process of trial and error.

28 Feb 2024

Developing a prognostic model for bladder urothelial cancer using oxidative stress signatures

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "Prognostic model development and molecular subtypes identification in bladder urothelial cancer by oxidative stress signatures."

28 Feb 2024

Unlocking coronavirus structure through M protein research

For centuries, coronaviruses have triggered health crises and economic challenges, with SARS-CoV-2, the coronavirus that spreads COVID-19, being a recent example.

28 Feb 2024

Medical Science News

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

UW researchers find similarities between diabetes and Alzheimer's protein clusters

Newly identified Enterococcus species shed light on antibiotic resistance spread

Rare gene mutations in hereditary Alzheimer's disease disrupt amyloid production, study shows

Corticosteroids may restore sense of smell in COVID-19 patients

Interdisciplinary project aims to decode human kinome in brain function and disease

Research uncovers key therapeutic target for reversing accelerated atherosclerosis in diabetes

Exercise, GLP-1 receptor agonist, or combined approach explored in year-long study

Association of estrogen-containing menopause hormonal therapy with COVID-19 mortality

Research finds link between unhealthy eating and chronic pain severity, calls for comprehensive dietary support

Research finds link between unhealthy eating and chronic pain severity, calls for comprehensive dietary support

Is posttraumatic epilepsy associated with long-term dementia risk?

NIH funds study on neural mechanisms behind autism and sound sensitivity

Sensory cues from the opposite sex affect aging in animals

Study demonstrates the deleterious effects of chronic cocaine use on functional brain networks

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

EPFL scientists uncover protein degradation mechanism preventing autoimmune reactions

UB research may offer a more streamlined approach to developing cancer drugs

Developing a prognostic model for bladder urothelial cancer using oxidative stress signatures

Unlocking coronavirus structure through M protein research

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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