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New handheld device promises rapid blood diagnostics

Patients who go to the doctor to provide a blood sample are typically faced with a needle and syringe and hours or days of waiting to get results back from a lab.

16 Oct 2024

Adenine base editors show potential to correct X-CGD-causing mutations

A collaborative effort between investigators at the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, demonstrates the potential of precise genome editing technologies, called adenine base editors, to correct disease-causing mutations in stem cells from patients with X-linked chronic granulomatous disease (X-CGD), a rare genetic disorder characterized by high susceptibility to infections.

16 Oct 2024

Molecular chaperones as key players in tumor suppressor stability

A new review was published in Oncotarget's Volume 15 on October 1, 2024, entitled, "Molecular chaperones: Guardians of tumor suppressor stability and function."

16 Oct 2024

Study reveals genetic factors affecting birth sex ratios

Each year, roughly the same numbers of boys and girls are born.

16 Oct 2024

UCLA and Parker Institute renew alliance to advance cancer immunotherapy

UCLA and the Parker Institute for Cancer Immunotherapy (PICI) have renewed their alliance to advance research in cancer immunotherapy and accelerate the development of curative treatments for the most difficult-to-treat cancers.

16 Oct 2024

Major donation fuels advances in ophthalmic artificial intelligence

The Icahn School of Medicine has announced a $5 million gift from the John and Daria Barry Foundation for the Center for Ophthalmic Artificial Intelligence (AI) and Human Health.

16 Oct 2024

Groundbreaking discovery offers hope for patients suffering from toxic epidermal necrolysis

A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis.

16 Oct 2024

Two programs found to control invasion and inflammation in segregated tumor cell populations

Understanding in depth how tumors evolve to become malignant is the objective of the latest study led by the Cell Plasticity in Development and Disease laboratory, directed by ángela Nieto at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche.

16 Oct 2024

Study provides detailed analysis of mRNA vaccine circulation and breakdown

A study led by researchers from RMIT University and the Doherty Institute has provided the first detailed analysis of how mRNA vaccines circulate and break down in the human bloodstream.

16 Oct 2024

Zebrafish could be used to explore the underlying mechanisms of Nager syndrome

Nager syndrome, or NS, is a rare genetic disease that affects the development of the face and limbs, usually causing anomalies in the bone structures of the jaws, cheeks, and hands.

16 Oct 2024

New blood test rapidly diagnoses heart attacks

With heart attacks, every second counts. A new blood test diagnoses them in minutes rather than hours and could be adapted as a tool for first responders and people at home.

16 Oct 2024

Understanding how men and women process pain differently

In a new study evaluating meditation for chronic lower back pain, researchers at University of California San Diego School of Medicine have discovered that men and women utilize different biological systems to relieve pain.

16 Oct 2024

Bacteriophages unveil auxiliary genes critical for infection

Viruses that infect bacteria—known as bacteriophages - could be used in a targeted manner to combat bacterial diseases.

16 Oct 2024

New drug targets identified for retinitis pigmentosa therapies

An international team of researchers has identified new drug targets for therapies that could benefit patients with different forms of retinitis pigmentosa and other inherited retinal diseases.

16 Oct 2024

Researchers develop decision tree to help clinicians predict genetic diagnoses in neurodevelopmental cases

A study identifies motor delay and hypotonia as key predictors of genetic diagnoses, aiding clinicians in neurodevelopmental care and genetic testing decisions.

16 Oct 2024

Researchers identify shared genetic variants between testosterone traits and PCOS

A genome-wide study reveals significant genetic overlap between polycystic ovary syndrome and testosterone-related traits, highlighting shared causal variants.

16 Oct 2024

AI models boost detection of cognitive decline in medical records, study finds

This study assesses large language models for early detection of cognitive decline, highlighting their strengths and limitations compared to conventional AI.

16 Oct 2024

Can soda taxes fight obesity? New research adds to the debate

Findings suggest the Philadelphia sweetened beverage tax may lower BMI and obesity prevalence in adults, offering insights into effective health interventions.

16 Oct 2024

Genetic risk factors for long-COVID uncovered in a large multi-ethnic study

Researchers identified genetic loci and phenotypes linked to long-COVID in the largest multi-ethnic GWAS, revealing increased risk factors for chronic conditions like fatigue, depression, and fibromyalgia.

16 Oct 2024

Antibody engineering drives innovation in drug development

Monoclonal antibodies (mAbs) are used to prevent, detect, and treat a broad spectrum of non-communicable and communicable diseases. Over the past few years, the market for mAbs has grown exponentially with an expected compound annual growth rate (CAGR) of 11.07% from 2024 (237.64 billion USD estimated at the end of 2023) to 2033 (679.03 billion USD expected by the end of 2033).

16 Oct 2024