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Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

Scientists explore the use of deep generative models in producing complete instances of as-yet undiscovered SARS-CoV2 Spike protein sequences. The resulting models substantially outperform a state-of-the-art generative model for protein sequences finetuned on SARS-CoV2 data.

14 May 2023

How have emergency medicine physicians' social media content and language changed during COVID-19, and can they provide insight into physician well-being?

Researchers analyzed Twitter to assess changes in the language during the coronavirus disease 2019.

12 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

Researchers longitudinally isolated immensely potent monoclonal antibodies from macaques vaccinated with COVID-19.

12 May 2023

COVID-19 that occurs after vaccination carries a much lower risk of severe illness

COVID-19 vaccination associated with lower rates of ICU admission and in-hospital mortality during the dominance of the Delta and Omicron variants.

11 May 2023

New antimicrobial coating material effectively kills bacteria and viruses

Researchers have used a common disinfectant and antiseptic to create a new antimicrobial coating material that effectively kills bacteria and viruses, including MRSA and Covid-19.

11 May 2023

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

An important genetic mechanism of drug resistance in one of the deadliest human malaria parasites has been identified in a new study published in Nature Microbiology.

11 May 2023

Testing policy change could reduce the burden of C. diff infections

A new study published today in the American Journal of Infection Control suggests that allowing bedside nurses to independently order testing for C. difficile significantly decreased the amount of time to receive test results as compared to requiring physician approval.

11 May 2023

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Researchers reported the increased transmissibility of the severe acute respiratory syndrome coronavirus 2.

11 May 2023

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Announcing a new article publication for Zoonoses journal. Aspergillus fumigatus infection in the lungs is accompanied by the recruitment of innate immune cells, phagocytosis, and the release of inflammatory factors.

11 May 2023

Can cognitive behavioral therapy target severe fatigue following COVID-19?

Researchers examined the efficacy of cognitive behavioral therapy (CBT) for severe fatigue after COVID-19.

11 May 2023

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Research compares the durability of neutralizing antibody responses among recipients of three different COVID-19 vaccines (BNT162b2, mRNA-1273, and Ad26.COV2.S) over a period of 6 months.

11 May 2023

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

In a recent article published in the journal Science Immunology, researchers in the United States performed a longitudinal cohort study in a golden hamster model to investigate the sensory-altering mechanisms induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection compared to an influenza A virus (IAV).

11 May 2023

Corona patients could easily perform the oxygen measurement themselves at home, study shows

When corona patients themselves measure the oxygen level in their blood at home, this is well applicable through the general practice.

10 May 2023

People living in the most deprived areas have higher risk of long COVID

New research has found that the risk of long COVID is strongly associated with area-level deprivation, with the odds of having long COVID 46% higher for people from the most deprived areas, compared to those in the least deprived areas.

10 May 2023

Cardiovascular risk reduction in type 2 diabetes: Study urges better use of life-saving therapies

Researchers explore the efficacy of current approaches to reduce the risk of cardiovascular events in patients with type 2 diabetes.

10 May 2023

Schlafen 12 identified as a novel HIV restriction factor

An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor.

10 May 2023

New AI-powered, laser-based breathalyzer can detect COVID-19 in real-time

With each breath, humans exhale more than 1,000 distinct molecules, producing a unique chemical fingerprint or "breathprint" rich with clues about what's going on inside the body.

10 May 2023

The potential variations in sperm quality of infertile patients during the COVID-19 pandemic

A recent study investigated how SARS-CoV-2 infection affected the semen quality of infertile men in Tunisia.

10 May 2023

Researchers develop new method of encapsulating fecal bacteria to treat serious intestinal infection

Clostridioides difficile infection causes severe diarrhea and results in the death of nearly 20,000 patients in Europe each year. It is one of the most common hospital-acquired infections. When it relapses, the disease must be treated by fecal microbiota transplantation.

10 May 2023

Disease/Infection News

Deep generative models to generate hypothetical SARS-CoV-2 spike sequences

How have emergency medicine physicians' social media content and language changed during COVID-19, and can they provide insight into physician well-being?

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Study identifies extremely potent monoclonal antibodies that neutralized multiple sarbecoviruses

COVID-19 that occurs after vaccination carries a much lower risk of severe illness

New antimicrobial coating material effectively kills bacteria and viruses

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

Testing policy change could reduce the burden of C. diff infections

Unlocking the secrets of Omicron: study reveals how unique spike mutations enable enhanced infectivity and resistance to immune barrier

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Can cognitive behavioral therapy target severe fatigue following COVID-19?

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Researchers show the effect of SARS-CoV-2 infection on somatosensory abnormalities in a hamster model

Corona patients could easily perform the oxygen measurement themselves at home, study shows

People living in the most deprived areas have higher risk of long COVID

Cardiovascular risk reduction in type 2 diabetes: Study urges better use of life-saving therapies

Schlafen 12 identified as a novel HIV restriction factor

New AI-powered, laser-based breathalyzer can detect COVID-19 in real-time

The potential variations in sperm quality of infertile patients during the COVID-19 pandemic

Researchers develop new method of encapsulating fecal bacteria to treat serious intestinal infection

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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