Cell Biology

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Study offers unprecedented insight into the mechanism of action of topo VI enzyme

The function of an enzyme, critical to most forms of life, has been revealed.

2 Feb 2022

Three different autism risk genes found to have similar effects on brain development

Autism spectrum disorder has been associated with hundreds of different genes, but how these distinct genetic mutations converge on a similar pathology in patients has remained a mystery.

2 Feb 2022

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Researchers at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA and the David Geffen School of Medicine at UCLA have developed a new mouse model of Huntington's disease that recapitulates more Huntington's disease-like characteristics than earlier models.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

'Genetic scissors' can give rise to unforeseen heritable mutations

CRISPR-Cas9, the "genetic scissors", creates new potential for curing diseases; but treatments must be reliable. In a new study, researchers have discovered that the method can give rise to unforeseen changes in DNA that can be inherited by the next generation.

2 Feb 2022

Researchers discover mechanism behind loss of smell in people with COVID-19

Researchers have discovered a mechanism that may explain why people with COVID-19 lose their sense of smell.

2 Feb 2022

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

The first generation of COVID-19 vaccines have been highly effective, but also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants.

2 Feb 2022

Gut bacteria transfer genes through sex to take vitamin B12, study shows

Your gut bacteria need vitamin B12 just as much as you do. Though DNA is usually passed from parent to child, new research shows gut bacteria transfer genes through "sex" in order to take their vitamins.

2 Feb 2022

Liver hormone suppresses alcohol consumption in primates, study shows

A hormone produced by the liver called fibroblast growth factor 21 (FGF21) suppresses alcohol consumption in primates, finds a study published February 1 in the journal Cell Metabolism.

1 Feb 2022

Researchers generate a complex kidney-like 3D tissue in the lab

A research team based in Kumamoto University (Japan) has created complex 3D kidney tissue in the lab solely from cultured mouse embryonic stem (ES) cells.

1 Feb 2022

Researchers investigate functional advantages of traveling brain waves during working memory

After more than a century of study, the significance of brain waves – the coordinated, rhythmic electrical activity of groups of brain cells – is still not fully known. An especially underappreciated aspect of the phenomenon is that waves spatially propagate, or "travel," through brain regions over time.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

Research uncovers how lactic acid disrupts the body's defense against tumors

In cancer research, it has long been known that lactic acid, or lactate, is produced in large quantities by cancer cells and that this lactic acid disrupts our defense against tumors.

29 Jan 2022

Study reveals role of a protein in healthy functioning of blood stem cells

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine.

28 Jan 2022

Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

An international team of researchers led by Karolinska Institutet in Sweden have discovered that a cell type in the central nervous system known as oligodendrocytes might have a different role in the development of multiple sclerosis (MS) than previously thought.

28 Jan 2022

Living human breast milk cells offer insight into breast cancer development

Researchers have explored the cellular changes that occur in human mammary tissue in lactating and non-lactating women, offering insight into the relationship between pregnancy, lactation, and breast cancer.

28 Jan 2022

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Hyaluronic acid, or HA, is a known presence in pancreatic tumors, but a new study from researchers at the University of Michigan Health Rogel Cancer Center shows that hyaluronic acid also acts as food to the cancer cells.

28 Jan 2022

ANU researchers identify why Th17 cells go rogue and promote the onset of multiple sclerosis

Researchers from The Australian National University (ANU) have identified why certain cells in the body, known as Th17 cells, go rogue and promote the onset of autoimmune diseases such as multiple sclerosis (MS).

27 Jan 2022

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

A protein known as Lefty pumps the brakes as human embryos begin to differentiate into the bones, soft tissues and organs that make us.

25 Jan 2022

Scientists explore how proteins bind with specific companions inside cells

Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of which interact with partner proteins to mediate upwards of 400,000 distinct interactions.

25 Jan 2022

Cell Biology

Study offers unprecedented insight into the mechanism of action of topo VI enzyme

Three different autism risk genes found to have similar effects on brain development

UCLA researchers develop first human genomic transgenic mouse model of Huntington's disease

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

'Genetic scissors' can give rise to unforeseen heritable mutations

Researchers discover mechanism behind loss of smell in people with COVID-19

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

Gut bacteria transfer genes through sex to take vitamin B12, study shows

Liver hormone suppresses alcohol consumption in primates, study shows

Researchers generate a complex kidney-like 3D tissue in the lab

Researchers investigate functional advantages of traveling brain waves during working memory

Study reveals potential mechanism for iron accumulation in the aging brain

Research uncovers how lactic acid disrupts the body's defense against tumors

Study reveals role of a protein in healthy functioning of blood stem cells

Oligodendrocytes may have a different role in the development of multiple sclerosis, study finds

Living human breast milk cells offer insight into breast cancer development

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

ANU researchers identify why Th17 cells go rogue and promote the onset of multiple sclerosis

‘Lefty’ protein pumps the brakes during initial stages of embryo differentiation

Scientists explore how proteins bind with specific companions inside cells

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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